Case Study: Anjo Kosei Hospital diagnoses rare neonatal diabetes faster with Wolters Kluwer UpToDate

How Pediatric resident diagnoses very rare case of neonatal diabetes mellitus

Anjo Kosei Hospital, where a pediatric resident was treating a one-month-old infant with vomiting, severe dehydration, metabolic acidosis, hyperglycemia, and ketosis, faced a rare and life-threatening diagnostic challenge. The team needed to quickly distinguish between common pediatric conditions and an uncommon cause of diabetic ketoacidosis in a neonate. Wolters Kluwer ELM Solutions’ clinical decision support resource, UpToDate, was used to search for the correct diagnosis and treatment.

Using UpToDate, Wolters Kluwer ELM Solutions helped the clinician identify neonatal diabetes mellitus at the first consultation and guide appropriate treatment without delay. The hospital was able to contact an external specialist, confirm a KCNJ11 gene mutation, and start effective therapy; the child’s blood glucose later stabilized on oral medication and he has continued to thrive with regular follow-up.

Anjo Kosei Hospital

Satoshi Hayano

Pediatric Cardiologist