Case Study: Methodist Hospital of Southern California achieves improved patient safety, reduced antibiotic use and lower sepsis rates with Veradigm

Commitment to patient safety earns top recognition

Methodist Hospital of Southern California, a 348‑bed community hospital in Arcadia, faced challenges reducing hospital‑acquired infections, unnecessary antibiotic use, and sepsis mortality while complying with federal and accreditation requirements. To support clinicians and enforce evidence‑based care, Methodist deployed the Allscripts Sunrise platform (along with Allscripts CareInMotion and EPSi) to provide configurable clinical decision support, order sets, and medication administration tools.

Using Allscripts’ configurable EHR and Medical Logic Modules, Methodist automated antibiotic stewardship, hard‑stop medication reconciliation, and sepsis alerts and order sets—resulting in a 20% reduction in days for eight of the top 10 antibiotics, a 15–20% drop in unnecessary antibiotic use (about $500,000 saved annually), a 70% reduction in C. diff rates (2015–2016), sepsis mortality under 20% versus ~35% nationally, and faster pharmacist workflows (48‑hour antibiotic timeout cut from 8 to 4 hours). Allscripts’ solutions directly supported these safety gains and contributed to Methodist’s five‑star CMS rating and $389,000 in Value‑Based Purchasing incentives.

Methodist Hospital of Southern California

Bala Chandrasekhar

Chief Medical Officer and Patient Safety Officer