Case Study: Wyss Institute advances brain drug delivery with Pluto Bio

Leveraging Pluto Bio for Brain Drug Delivery Wyss Institute Brain Targeting Program

The Wyss Institute at Harvard University's Brain Targeting Program faced the significant challenge of poor drug delivery across the blood-brain barrier, which contributes to high failure rates in clinical trials for brain diseases. To address this, they partnered with vendor Pluto Bio to utilize its multi-omics software platform for target discovery.

Pluto Bio's solution involved analyzing multi-omics data and curated literature evidence, integrating these findings with expert insight from Wyss scientists. This collaboration efficiently identified and prioritized transport targets, leading to an advancement in developing antibody-based brain transport shuttles with the potential to revolutionize treatments for brain diseases.

Wyss Institute