Case Study: Pure Protein achieves seamless HLA peptide binding assay continuity with Molecular Devices SpectraMax Paradigm

Pure Protein validates 58 HLA alleles with Molecular Devices

Pure Protein, LLC, a company specializing in high-accuracy peptide binding assays for immunotherapy research, faced a major challenge when their two-decade-old Molecular Devices Analyst AD microplate reader reached the end of its service life. They needed a new instrument with the extreme sensitivity to match their established Fluorescence Polarization (FP) assay protocols for validating HLA peptide epitope targets without invalidating years of historical data.

Molecular Devices provided the solution with the SpectraMax Paradigm Multi-Mode Microplate Reader. After extensive on-site testing, the new instrument produced virtually identical assay results, ensuring data continuity and eliminating the need for system re-qualification. This seamless transition allowed Pure Protein to not only maintain its research integrity but also significantly expand its capabilities, successfully developing FP-based assays for a world-record 58 different HLA alleles.

Pure Protein, LLC