Case Study: Stanford University School of Medicine achieves breakthrough cystic fibrosis insights with JMP

Stanford Researcher Challenges Assumptions About Cystic Fibrosis

Stanford University School of Medicine researcher Rabin Tirouvanziam and the Herzenberg Lab used JMP statistical software to analyze complex cystic fibrosis data and challenge the long-held belief that neutrophils were merely bystanders in lung disease. Their challenge was to determine whether the course of cystic fibrosis and other diseases could be changed by identifying and targeting neutrophil activity.

With JMP, Stanford University School of Medicine evaluated treatment responses and explored links between genetic and other markers tied to neutrophil function. The analysis showed live neutrophils are central to cystic fibrosis onset and progression, revealed two key survival pathways, and helped point to treatable targets and new therapy options, with ongoing studies suggesting the findings may help extend lives.

Stanford University School of Medicine

Rabin Tirouvanziam

Researcher and Instructor