Case Study: North Carolina State University achieves clear insights into how habitat and lifestyle affect gene expression with JMP Genomics

NCSU research in habitats, houses or tents, lifestyle affects health

North Carolina State University researchers studying red wolves and human populations wanted to understand how habitat and lifestyle influence genetic expression and disease patterns. Using JMP Genomics, they analyzed microarray, genotyping, and expression data to compare wild versus captive wolves and three Berber populations living in different environments.

JMP Genomics helped the team perform rigorous statistical analysis, quality control, normalization, and pattern discovery across large datasets. The results showed clear links between environment or lifestyle and gene expression: captive wolves had significant expression differences suggesting stress and immune effects, and in humans, lifestyle explained about one third of the gene expression differences.

North Carolina State University

Youssef Idaghdour

North Carolina State University