Case Study: Large U.S. medical center achieves rapid sepsis detection and 80% nurse compliance improvement with Health Catalyst

How to Improve Sepsis Diagnosis and Outcomes through Innovative Healthcare Analytics

United States Healthcare Provider, a large medical center, faced persistent challenges diagnosing sepsis early, tracking nurses’ compliance with manual screening protocols, and lacked an analytics platform to establish baselines or measure intervention impact. To address these gaps they partnered with Health Catalyst, deploying its Late-Binding™ Data Warehouse and the Population Analytics Advanced Application – Sepsis Module along with installation and improvement services.

Health Catalyst implemented an enterprise data warehouse, the Sepsis Module, and a cross‑functional team to build a sepsis registry and analytics platform in 10 weeks, enabling real-time measurement and improvement. The platform produced measurable gains—a documented 80% relative increase in nurses’ screening compliance—and supported development and testing of an electronic early-sepsis detection algorithm (which aims to cut RN manual screening time by an estimated 2,500 hours per month), while providing a scalable foundation to track interventions and outcomes.