Case Study: Just Biotherapeutics achieves automated high-throughput MAM and improved QC with Genedata Expressionist

Automated Software-Driven MAM Implementation for Biotherapeutic Characterization

Just Biotherapeutics, an integrated design company focused on accelerating biotherapeutics development, faced bottlenecks in implementing mass-spectrometry-based multi-attribute method (MAM) characterization: large MS data volumes limiting throughput, high rates of false-positive identifications, difficulty detecting unexpected peaks, and fragmented data/reporting workflows. To overcome these challenges the company adopted Genedata’s solution, Genedata Expressionist.

Genedata implemented automated, metadata-driven MS data‑processing workflows in Genedata Expressionist with intelligent filtering, dynamic new-peak detection, a centralized knowledge base, and configurable reporting. The result: Just Biotherapeutics can process hundreds of samples per week with minimal manual intervention, substantially reduce false positives and review time, improve detection of unexpected contaminants, and produce compliant automated reports—boosting throughput, productivity, and cross-team knowledge sharing.

Just Biotherapeutics

Richard Rogers

Senior Scientist