Case Study: Fulcrum Therapeutics achieves secure, GxP-compliant centralized data collaboration with Egnyte

Fulcrum Therapeutics Shares Insights on Collaboration and Compliance

Fulcrum Therapeutics is a Cambridge‑based biotech developing small‑molecule treatments that modulate gene expression to address the root causes of genetically defined rare diseases. Rapid growth, extensive outsourcing, and high‑content datasets (imaging, RNA‑seq, single‑cell data) created challenges: massive, varied files scattered across repositories, the need for GxP‑compliant security, and a single source of truth to support internal and external collaboration—especially during remote work.

Fulcrum implemented Egnyte, integrated with Science Exchange, to automate folder creation for external requests, centralize compliant storage, and standardize access controls. The solution eliminated time spent hunting for data, preserved institutional knowledge, enabled secure sharing and remote collaboration, and gave scientists seamless access to large datasets for analysis and machine‑learning, accelerating insight generation and scalable drug‑development workflows.

Fulcrum Therapeutics

Chris Moxham

Senior Vice President of Discovery Research