Case Study: Sarepta Therapeutics accelerates rare disease clinical trials with eClinical Solutions

Sarepta Accelerates Data Review for Rare Disease

Sarepta Therapeutics, a company specializing in gene therapies for rare diseases, needed to accelerate its clinical trials for Duchenne muscular dystrophy to meet urgent patient needs. They faced a challenge in managing an avalanche of longitudinal patient data, requiring rapid data review and analysis to quickly assess treatment safety and efficacy. To manage this, Sarepta partnered with eClinical Solutions for its biometrics services and utilized the elluminate Clinical Data Cloud.

eClinical Solutions implemented a data-centered solution, configuring Rave EDC and leveraging the elluminate platform to provide a centralized, clean source of truth for all data. This partnership increased standardization, with 93% reuse of forms and edit checks, and instituted a continuous data review process where 95% of data is always reviewed. The results included faster database locks, more efficient study starts, and the ability to rapidly analyze clean data, ultimately accelerating Sarepta's clinical trial process.

Sarepta Therapeutics

Elizabeth Thompson

Associate Director, Clinical Data Management