Case Study: The Institute of Cancer Research achieves Thermal Shift Assay processing in under one hour (down from half a day) with Dotmatics Vortex

How Vortex speeds up data processing

The Institute of Cancer Research (ICR) — specifically its Cancer Therapeutics Unit — faced a laborious, error-prone workflow for processing Thermal Shift Assay data, relying on Excel and GraphPad Prism with time-consuming copy‑and‑paste steps that created a half‑day bottleneck. To address this, the Unit engaged Dotmatics and its Vortex data visualisation and analysis solution.

Dotmatics implemented Vortex as a centrally provisioned, script-driven workflow (with Browser integration and access to the Dotmatics add‑on pack and script share) and linked it to R via Python scripting, replacing manual Excel steps with reproducible, automated processing. The change reduced Thermal Shift Assay processing from half a day to less than one hour, improved reproducibility and error reduction, and made best‑practice scripts easy to distribute across the team.

The Institute of Cancer Research

Fiona Jeganathan

Institute of Cancer Research