Case Study: European sponsor achieves streamlined, compliant eCOA and imaging for a global ulcerative colitis trial with Clario

Clario simplifies complex eCOA and imaging GI study with single-vendor solution

European Sponsor ran a three‑year, global ulcerative colitis study with more than 300 participants across North and South America, Europe and APAC and faced challenges in assessing disease severity reliably: maintaining participant motivation and compliance, ensuring consistent endoscopic image quality and reader scoring, and integrating eCOA and imaging workflows. Clario was engaged to collect both remote and in‑clinic eCOA and endoscopy imaging primary endpoint data using an integrated eCOA and imaging solution.

Clario delivered a single‑vendor, science‑led solution—eDiary with alerts and engagement tools, standardized endoscopic video acquisition/QC and centralized reading, site training and 24/7 multilingual support, and a single portal with integrated Mayo score and trial oversight. The result was simplified data collection, integration and reporting from one partner, regulatory‑compliant, standardized clinical data, reduced participant burden through a user‑friendly app, and real‑time visibility of Mayo scores and trial progress—supporting the successful execution of the three‑year, 300+ participant study.