Case Study: Intellia Therapeutics achieves centralized plasmid registration and streamlined request triaging with Benchling

Streamlining Registration and Requests for Gene Editing

Intellia Therapeutics, a developer of CRISPR/Cas9 in vivo and ex vivo gene‑editing therapeutics, struggled with fragmented processes: registration was spread across SharePoint spreadsheets, emails, and paper, plasmid repositories couldn’t be tracked or kept current, and the lack of a formal request system led to lost or incomplete requests and slow, error‑prone work.

By adopting Benchling, Intellia centralized registration with standardized plasmid and entity lists, implemented Request Management to triage and track requests, and used Workflow Management to trace upstream entities to outcomes. The result was reliable, easily shared data, increased throughput and product quality, and actionable R&D insights—such as identifying which bio‑vector produced a particularly effective protein batch.

Intellia Therapeutics