Case Study: Grifols achieves 83% reduction in change request processing time with Appian

Grifols - Customer Case Study

Grifols, a global leader in the plasma industry with more than 250 donor centers and over 75 years of experience, faced a costly and time-consuming change control challenge: the Plasma Division processed more than 700 Change Requests (CRs) annually through manual verification, siloed email and spreadsheet workflows, and extensive back-and-forth among administrators and reviewers. This ad hoc process created delays, limited visibility, and compliance risks for impact analyses, approvals, and document handling.

Using Appian’s low-code platform, Grifols deployed an end-to-end change control solution in 18 weeks that enabled electronic CR submission, automatic CR numbering, suggested task assignees and due dates, automated notifications, compliant electronic signatures, a unified document repository, and real-time visibility with full audit trails. The result was an 83% reduction in data entry and filing time (from ~180 to ~30 minutes per CR), a 62.5% reduction in tracking and follow-up (saving ~2,010 labor hours per year), reduced weekly tracking time from 8 to 3 hours, 75% faster development, and a shift from paper-based to paperless processes — all delivered on budget.

Grifols