Case Study: UK-based Phase‑1 clinical research institution achieves 150x faster reporting and secure CRM for 260,000+ volunteers with Altoros

Optimizing Data Management and Reporting for 500+ Clinical Trials

The customer, a UK‑based Phase‑1 clinical research organization accredited by the Medicines and Healthcare products Regulatory Agency that has run 500+ clinical trials, was operating a legacy ASP.NET WebForms CRM holding 260,000+ volunteer records and onboarding 400+ new volunteers monthly. Facing scalability, performance and security challenges, the organization engaged Altoros to migrate and modernize the CRM (moving to a modern .NET stack with an Angular/TypeScript front end) while preserving data integrity and compliance.

Altoros migrated and refactored the 12‑module system, applied data normalization and partitioning, implemented role‑based access via IdentityServer4/Active Directory, integrated Twilio/DocuSign/Dotdigital, and built CI/CD pipelines and automated testing. The work secured and migrated all sensitive data without loss, cut report generation from 5 minutes to 2 seconds (≈150x faster), sustained the 260k+ volunteer base with 400+ monthly additions, reduced feature delivery to 2 minutes, and saved up to $600/year on Twilio usage.