Case Study: Revolution Medicines cuts advanced email threats by 99.9% and automates defenses with Abnormal AI

Revolution Medicines Guards Its Cancer Research and Patients With Abnormal

Revolution Medicines, a Redwood City biotech developing RAS(ON) inhibitors, faced sophisticated email threats that put research, IP and patient data at risk. Using Microsoft 365 and a legacy SEG left the SOC reactive and overwhelmed by false positives, spam and graymail. To address this, RevMed turned to Abnormal AI, deploying its inbound email security, account takeover protection and AI Security Mailbox capabilities to reduce manual remediation and protect researchers and patients.

Abnormal AI’s human-behavioral AI and automation filtered user-specific graymail (over 100K messages/month), integrated with CrowdStrike, and shifted RevMed from reactive response to proactive threat hunting. Within 30 days Abnormal AI cut advanced threats reaching inboxes by 99.9%, achieved 100% automated email remediations, and saved 163 company hours on graymail — freeing the SOC to focus on threat hunting and enabling researchers to concentrate on science.

Revolution Medicines

Carlos Escobar

VP of Information Security